A report on the investigation into the 1989 murder of 16-year-old Amy Weidner, a young mother who was beaten, sexually assaulted and killed in the bedroom of her Indianapolis, Indiana home while she and Emily, her 2-year-old daughter, were home alone. Even though there was a bloody handprint on the bedroom wall, none of the leads led to an arrest and the case grew cold.

Was it murder at the hands of a man with a taste for bondage and domination, or was it an accident? Troy Roberts and 48 HOURS investigate the events leading to the death of University of New Hampshire sophomore Lizzi Marriot. It's a case that explores the sinister side of BDSM - bondage and sadomasochism. It exposes a man who fantasized about murder and the teenager who got caught up in his world for just one night.

A report on the investigation into the death of Alabama real estate agent Angel Downs, who was found dead from a gunshot wound to the head, by her own weapon, outside her Gulf Shores, Alabama condo in 2010. At the time of her death, she was involved with Stephen Nodine, a well-liked Alabama politician with connections in Washington D.C. Though married and the father of a young son, Nodine dated Downs for six years. Friends and family say Angel wanted him to get a divorce, but he refused to give up his double life.

For more than four decades, Evelyn McCabe wondered who killed her son, John. He was 15 years, six months and two weeks old when she let him attend a Knights of Columbus dance. He never made it to 15 years, six months, two weeks and one day old. After the dance, John was murdered. Richard Schlesinger and 48 Hours investigate the murder of John McCabe and his family's decades-long quest to find out what really happened to their son.

The team must intervene when Paige and Ralph are on a sabotaged, runaway subway train; Toby tries to impress Happy during his first boxing match.

A report about the 2011 shooting death of Greg Williams, and the question of whether he was killed with his own gun by an intruder inside his suburban Dallas home - as his wife Michele Williams has claimed - or if Michele herself was guilty of the crime.

All new: Did a cartoon play a part in the death of a California man? "48 Hours" correspondent Richard Schlesinger investigates.

The investigation into the 2008 murder of Juliana Redding, an aspiring actress and model and the subsequent trial. Redding was found dead in her Santa Monica, California home. According to authorities, the killer hoped to erase any evidence of the crime; trying to blow up the entire crime scene by leaving the gas on and a candle burning. This did not happen, and there was plenty of DNA evidence remaining at the scene.

A review of the case against Cal Harris, whom prosecutors in Northern New York believe is guilty of killing his estranged wife Michele, to preserve his fortune. This followup report includes the first interview with Cal Harris. Twice, he has been tried and found guilty, and twice those convictions have been overturned.

Police launch a massive manhunt when a bride-to-be disappears. Is it a crime or the wedding jitters? Also, a Mexican drug lord claims his cartel is a necessary evil that protects people from even bloodier rivals.